postoperative delirium
Conditions
Interventions
Gold Standard:CAM-ICU or 3D-CAM
model 
of 
based 
on 
MRI 
and 
machine 
learning 
in 
patients
Sponsors
Huadong Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Patients scheduled to undergo non-cardiac surgery and go to ICU postoperatively; 2) Aged >= 60 years; 3) ASA class III-IV; 4) Right handedness.
Exclusion criteria
Exclusion criteria: 1. Patients with central nerve system diseases and/or psychosomatic disease before surgery; 2. patients with history of agitans paralysis; 3. patients with history of cerebrovascular accident; 4. patients scheduled to undergo brain surgery; 5. patients taking neural psychiatric drugs such as sedative and antidepressant; 6. alcohol abuser or drug dependence; 7. patients with impairment of liver or kidney function; 8. patient who are not able to complete test because of impairment of vision or hearing of communication. 9. patients who can not perform MRI because of implantation of metal or heart pacemaker; 10. patients who can not finish MRI because of action inconvenience such as fracture; 11. patients with claustrophobia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional connectivity;voxel based morphometry;fractional anisotropy;SEN, SPE, ACC, AUC of ROC, PPV, NPV; | — |
Countries
China
Contacts
Public ContactWeidong Gu
Huadong Hospital Affiliated to Fudan University
Outcome results
None listed