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To explore the role of vasoactive peptide CGRP and PACAP-38 in the occurrence and diagnosis of migraine in children

To explore the role of vasoactive peptide CGRP and PACAP-38 in the occurrence and diagnosis of migraine in children

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043157
Enrollment
Unknown
Registered
2021-02-07
Start date
2021-11-01
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine

Interventions

Case group:Nil
Control group:Nil

Sponsors

Qilu Hospital of Shandong university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for the patient group: 1. Ages 0-18, male or female; 2. ICHD-3 migraine without aura, migraine with aura, chronic migraine diagnostic criteria; 3. No other serious health threat except for research diseases; 4. From January 2021 to January 2022, he was admitted to pediatrics outpatient and inpatient Department of Qilu Hospital, Shandong University; 5. Informed consent of the patients and their families on the purpose, significance, risks and benefits of the study. Inclusion criteria of the health group: 1. Ages 6-18, male or female; 2. No symptoms and signs of migraine and other types of headache; 3. No other serious health threats; 4. From January 2021 to January 2022, he was admitted to pediatrics outpatient and inpatient Department of Qilu Hospital, Shandong University; 5. Informed consent of the patients and their families on the purpose, significance, risks and benefits of the study.

Exclusion criteria

Exclusion criteria: 1. Presence of drug ingestion; 2. Autoimmune and neuroinflammatory diseases; 3. Mast cell-related diseases; 4. Allergies; 5. Intracranial masses; 6. Congenital or genetic abnormalities and chronic diseases; 7. Mental disorders; 8. Physical inadmissio; 9. Other types of primary and secondary headaches; 10. Lack of informed consent by family members and individuals.

Design outcomes

Primary

MeasureTime frame
Calcitonin gene related peptide, CGRP;Pituitary Adenylate Cyclase Activating Polypeptide-38, PACAP-38;

Countries

China

Contacts

Public ContactLiu Xinjie

Qilu Hospital of Shandong University

liuxinjie-ert@163.com+86 18560086300

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026