Skip to content

The research on the mechanism of 'liver-soothing with blood-nourishing and detoxifying' therapy in the treatment of psoriasis patients with depressive state based on inflammation pathway mediated by HPA-MC

The research on the mechanism of 'liver-soothing with blood-nourishing and detoxifying' therapy in the treatment of psoriasis patients with depressive state based on inflammation pathway mediated by HPA-MC

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100043142
Enrollment
Unknown
Registered
2021-02-05
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis

Interventions

Sponsors

Beijing Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for psoriasis vulgaris, and all are in the stationary phase; 2. Meet the syndrome differentiation criteria of Psoriasis Vulgaris with Blood Dryness and Liver-Stagnation Syndrome (All the selected patients have been determined by at least two associate chief physicians or experts with titles above to determine whether they belong to the Blood Dryness and Liver-Stagnation Syndrome); 3. Adopt the DSM-IV axis I mental disorder clinical interview (non-patient version) to exclude any disease or disorder in the DSM-IV diagnostic criteria, and no mental disorder in the first-degree relatives; 4. Hamilton Depression Scale (HAMD) score >= 7 points, and Hamilton Anxiety Scale (HAMA) score < 7 points; 5. Age range 18-60 years old; 6. Volunteer to participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who have received immunomodulators or hormones systematically in the past month; 2. Pregnant and lactating women; 3. Brain organic diseases or clear physical diseases; 4. History of head trauma, loss of consciousness for more than 1 hour; or obvious mental retardation; 5. Patients with a clear history of schizophrenia and history of alcohol and drug abuse or dependence; 6. Patients with severe depression, HAMD scale score >= 35 points; 7. There are metal foreign bodies in the body (such as metal dentures, pacemakers, etc.) that affect the magnetic resonance examination; 8. Patients with severe heart, lung, liver, kidney, digestive tract and other visceral diseases.

Design outcomes

Primary

MeasureTime frame
PASI;

Countries

China

Contacts

Public ContactZhang Guangzhong

Beijing Hospital of Traditional Chinese Medicine

zhgzh62000@126.com+86 15901132668

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026