Clinical study on the application of PRF / phytoestrogen daidzein complex method in post menopausal women with osteoporosis after tooth extraction

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100043116

Enrollment

Unknown

Registered

2021-02-05

Start date

2021-03-01

Completion date

Unknown

Last updated

2021-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar bone loss

Interventions

Blank control group:Do nothing

Negative control group:Place PRF

experience group:Placement of PRF + DAI complex

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Women aged 50-70 years with physiological menopause; 2. Subjects diagnosed as estrogen induced osteopenia by endocrinologists (2017 diagnostic criteria); 3. Subjects with periodontal health or mild chronic periodontitis in stable stage (standard version number); 4. Subjects who can tolerate tooth extraction and site preservation; 5. Subjects with strong compliance are willing to accept this clinical study.

Exclusion criteria

Exclusion criteria: 1. Subjects who are using estrogen, bisphosphonates or other related drugs at present; 2. Subjects with history of limb immobilization or long-term bedridden;

Design outcomes

Primary

Measure	Time frame
Mesial alveolar ridge height;	—

Countries

China

Contacts

Public ContactQi Li

Department of Stomatology, Affiliated Hospital of Inner Mongolia Medical University

gyjlq@163.com+86 15247131983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026