Sepsis
Conditions
Interventions
Sponsors
Beijing University of Chinese Medicine Shenzhen Hospitai
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients meeting the diagnostic criteria of sepsis; 2. Patients with gastrointestinal dysfunction; 3. Patients who meet the diagnostic criteria of Shaoyang Jianli syndrome; 4. Patients aged 18-80 years old; 5. Informed consent signed by patients or their families.
Exclusion criteria
Exclusion criteria: 1. Incomplete observation items, lack of important observation index items, resulting in unable to evaluate the efficacy and safety index; 2. The subjects who used some prohibited drugs or other drugs that affect the efficacy and safety evaluation during the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM Syndrome Points;Gastrointestinal dysfunction score;Intestinal flora detection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum inflammatory factors (TLR-4, NF-kB, IL-6, PCT, CRP);Serological indicators of intestinal mucosal barrier function (I-FABP, ZO-1, Occludin, LPS);Immunological index (CD4+, CD8+, Treg, Th17, IL-10);APACHE-II??;Marshall??;28-day mortality;ICU hospital stay; | — |
Countries
China
Contacts
Public ContactPing Wang
Beijing University of Chinese Medicine Shenzhen Hospitai
Outcome results
None listed