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Study on the electroencephalographic mechanism of short-term spinal cord electrical stimulation for herpes zoster-associated neuralgia

Study on the electroencephalographic mechanism of short-term spinal cord electrical stimulation for herpes zoster-associated neuralgia

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043097
Enrollment
Unknown
Registered
2021-02-05
Start date
2021-02-06
Completion date
Unknown
Last updated
2021-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

herpes zoster-associated neuralgia

Interventions

SCS group:Short-term spinal cord stimulation
control group:none
disease group:none

Sponsors

The Third Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Refer to clinical Diagnosis and Treatment Guide-Dermatology and Venereal Diseases Volume (edited by Chinese Medical Association, People's Medical Publishing House, 2006). Before rash can have tired, low fever, whole body unwell, anorexia wait for prodrome symptom.The affected area has neuralgia, skin hypersensitivity.The main sites of study were the intercostal nerve, brachial plexus nerve and the skin of the sciatic nerve innervation area.The rash is from concentrated miliary to large blister of mung bean on erythra, and the blister fluid is often clear.The rash is usually unilateral and generally does not exceed the midline of the body.Skin can be healed after pigment change, necrotic ulcer can be left scar. 2. Patients were enrolled in the study regardless of gender, aged > 18 and in post-herpetic neuralgia, and in healthy subjects matched by age and sex. 3. All patients were treated with normal medication and still accompanied by severe neuralgia (visual analog scale (VAS) >= 5). 4. All patients in the study signed informed consent forms.

Exclusion criteria

Exclusion criteria: Patients with tumor or history of tumor, mental illness, severe cardiovascular and cerebrovascular diseases, combined with pregnancy, other chronic pain, liver and kidney dysfunction, coagulation dysfunction, unable or unwilling to cooperate with the study.

Design outcomes

Primary

MeasureTime frame
visual analog scale;eeg data;Simplified McGill Pain Questionnaire-2;

Secondary

MeasureTime frame
Pittsburgh sleep quality index;Baker Anxiety Scale;Baker Depression Scale;

Countries

China

Contacts

Public ContactHan Rui

The Third Xiangya Hospital, Central South University

hrmyeye@163.com+86 13787102041

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026