herpes zoster-associated neuralgia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Refer to clinical Diagnosis and Treatment Guide-Dermatology and Venereal Diseases Volume (edited by Chinese Medical Association, People's Medical Publishing House, 2006). Before rash can have tired, low fever, whole body unwell, anorexia wait for prodrome symptom.The affected area has neuralgia, skin hypersensitivity.The main sites of study were the intercostal nerve, brachial plexus nerve and the skin of the sciatic nerve innervation area.The rash is from concentrated miliary to large blister of mung bean on erythra, and the blister fluid is often clear.The rash is usually unilateral and generally does not exceed the midline of the body.Skin can be healed after pigment change, necrotic ulcer can be left scar. 2. Patients were enrolled in the study regardless of gender, aged > 18 and in post-herpetic neuralgia, and in healthy subjects matched by age and sex. 3. All patients were treated with normal medication and still accompanied by severe neuralgia (visual analog scale (VAS) >= 5). 4. All patients in the study signed informed consent forms.
Exclusion criteria
Exclusion criteria: Patients with tumor or history of tumor, mental illness, severe cardiovascular and cerebrovascular diseases, combined with pregnancy, other chronic pain, liver and kidney dysfunction, coagulation dysfunction, unable or unwilling to cooperate with the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analog scale;eeg data;Simplified McGill Pain Questionnaire-2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index;Baker Anxiety Scale;Baker Depression Scale; | — |
Countries
China
Contacts
The Third Xiangya Hospital, Central South University