spinal-induced hypotension
Conditions
Interventions
methoxamine group:The corresponding dose of methoxide (1mg, 1.5mg, 2mg, 2.5mg, 3mg, 3.5mg IV) shall be given according to the drug reaction of the previous case
Sponsors
West China Second University Hospital, Sichuan University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Parturients, American Society of Anesthesiologists physical status (ASA <= II), singleton pregnancy, scheduled for elective cesarean delivery, undertaken combined spinal-epidural anesthesia.
Exclusion criteria
Exclusion criteria: Body mass index > 30kg/m2, height 170 cm, anemia (hemoglobin < 9 g/dl ), known cardiovascular or cerebrovascular disease, pre-existing or pregnancy-induced hypertension, diabetes mellitus, fetal abnormality, monoamine oxidase inhibitors undertaken or contraindication to spinal anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the success of intermittent boluses of the assigned dose of methoxide to prevent hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| the incidence of bradycardia;the incidence of reactive hypertension;umbilical blood pH; | — |
Countries
China
Contacts
Public ContactXuemei Lin
Department of Anesthesiology, West China Second University Hospital,Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University
Outcome results
None listed