Effects of antibiotics on fecal short-chain fatty acids, intestinal flora and fecal autoinducer-2 levels in preterm infants

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100043065

Enrollment

Unknown

Registered

2021-02-04

Start date

2021-02-04

Completion date

Unknown

Last updated

2021-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intestinal flora in preterm infants

Interventions

Antibiotic use in preterm infants less than 30 weeks of age:Nil

Preterm infants less than 30 weeks old without antibiotics or only prophylactic use of antibiotics after birth:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The preterm infants who are admitted to the newborn diagnosis and treatment center of Children's Hospital Affiliated to Chongqing Medical University will primary included this study if these infants with gestational age less than 30 weeks, birth weight less than 1500g are admitted within 24 hours after birth.

Exclusion criteria

Exclusion criteria: (1) Children with congenital gastrointestinal malformation (such as congenital intestinal atresia, hypercolon malrotation, etc.); (2) Patients who Abandoning treatment during hospitalization; (3) Patients who did not complete the determination of intestinal flora and fecal SCFAS AI-2; (4) Patients unwilling to participate in this study.

Design outcomes

Primary

Measure	Time frame
short chain fatty acids;intestinal flora;	—

Countries

China

Contacts

Public ContactLi Luquan

Newborn Diagnosis and Treatment Center of Children's Hospital Affiliated to Chongqing Medical University

liluquan123@163.com+86 17323882725

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026