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Effect of Kuanxiong Aerosol on Patients with Prehospital Chest Pain: a Randomized Controlled Study

Effect of Kuanxiong Aerosol on Patients with Prehospital Chest Pain: a Randomized Controlled Study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100043042
Enrollment
Unknown
Registered
2021-02-04
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chest pain

Interventions

EA group:Kuanxiong Aerosol
control group:Nitroglycerin Aerosol

Sponsors

Department of Emergency Medicine of Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with pre-hospital symptoms of "chest tightness", "chest pain", "suffocating" and other emergency department visits; 2. Age 25 ~ 80 years old, gender is not limited; 3. Patients with clear consciousness and can clearly express their chest tightness and pain symptoms; 4. Volunteer to participate in the clinical trial, understand and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with unstable vital signs (such as hypotension) and in need of emergency rescue; 2. Traumatic chest pain; 3. Before emergency treatment, patients felt "chest tightness", "chest pain", "asthma" and other symptoms were significantly relieved or had used some drugs (such as nitroglycerin) related to the relief of "chest tightness", "chest pain", "asthma" and other symptoms from the onset of symptoms until before enrollment; 4. Patients with severe liver and kidney dysfunction, malignant tumors, endocrine system, hematopoietic system diseases or other serious diseases; 5. Patients with complications that can increase mortality: such as cardiac shock, severe ventricular arrhythmia, complete atrioventricular block, obstructive cardiomyopathy, cardiac tamponia, pulmonary embolism, etc.; 6. Known or suspected of wide chest aerosol, nitroglycerin aerosol drug ingredients allergy;People allergic to alcohol. 7. Patients in a special period, such as lactation or pregnancy; 8. The combination of mental consciousness abnormal; 9. Participated in other clinical trials in the past 1 month; 10. Other patients whom the clinician deems unsuitable for the test.

Design outcomes

Primary

MeasureTime frame
Degree and duration of relief of chest tightness and pain;

Secondary

MeasureTime frame
Number of use of Kuanxiong Aerosol or Nitroglycerin Aerosol within 3 months after enrolment;Number of chest tightness and pain within 3 months;Call again for "chest tightness and pain" for 120/ visits within 3 months;The number of stays/hospitalizations due to "chest tightness and pain" again within 3 months;Cost of single visit and emergency observation time for non-hospitalized patients;

Countries

China

Contacts

Public ContactDing Banghan

Guangdong Provincial Hospital of Chinese Medicine

banghanding@139.com+86 20-81887233

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026