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Perioperative type II thoracic nerve block and postoperative recurrence in breast cancer: a randomized controlled trial

Application of ultrasound-guided type II thoracic nerve block in breast cancer surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100043031
Enrollment
Unknown
Registered
2021-02-04
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

General Group : General anesthesia
General+PECS-2 Group : general anesthesia with Pecs II block

Sponsors

Department of Anesthesiology, Cangzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
19 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients with BMI of 18.5-24.0 kg / m2, ASA grade I-III, 2. Patients without chronic pain; 3. Patients with a history of abdominal surgery; 4. Those patients with contraindications of nerve block; 5. Patients with normal coagulation function.

Exclusion criteria

Exclusion criteria: 1. Subjects younger than 18 years old were included; 2. Subjects with other cancer history; 3. Subjects with previous operation history; 4. Subjects with respiratory diseases; 5. Subjects with heart disease; 6. Subjects with drug allergy during operation; 7. Subjects who have received chemotherapy or radiotherapy in the last 8 weeks; 8. Steroid or opioid use and alcohol dependence.

Design outcomes

Primary

MeasureTime frame
Survival without distant recurrence;Recurrence-free survival;Overall survival;VAS score;Respiratory function;Incidence of neuropathic pain;Quality of life scale score;

Secondary

MeasureTime frame
Number of analgesic pump compressions within 48 hours;Nausea and vomiting score;Restlessness during recovery;Postoperative delirium (POD) situation;24 h postoperative recovery quality score;Hospital stay;Nerve Block Adverse Reaction;

Countries

China

Contacts

Public ContactCui xiuling

Department of Anesthesiology, Cangzhou Central Hospital

Zhangbo19970418@163.com+86 15103172870

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026