Chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 40 to 85 years; 2. Patients who meet the diagnostic criteria of COPD comprehensive evaluation group B, C and D, and they are in the acute exacerbation stage; 3. Patients who are diagnosed with moderate to severe AECOPD; 4. Patients who meet the Chinese medicine syndrome classification of phlegm heat obstructing lung; 5. Patients who sign the written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Other respiratory diseases: bronchial asthma, bronchiectasis, bullae, pleural effusion, active tuberculosis and other lung diseases; 2. Severe or uncontrollable diseases: hematological diseases; liver dysfunction (ALT or AST >=3 ULN, total bilirubin>=1.5 ULN), renal dysfunction (serum creatinine >177 umol/L or 2mg/dl), congestive heart failure (III-IV); immune deficiency, tumor, organ or bone marrow transplantation, HIV or immunosuppressive therapy in recent 3 months; 3. Patients with diabetes or impaired glucose tolerance; 4. Systemic glucocorticoids were needed in recent 3 months; 5. Patients with confirmed history of alcohol, drug abuse or mental illness; 6. Patients with dysphagia or gastrointestinal disease affecting drug absorption (reflux esophagitis, chronic diarrhea, inflammatory bowel disease, intestinal tuberculosis, gastrinoma, short bowel syndrome, after subtotal gastrectomy); 7. Patients who have known hypersensitivity to the study medication or some of its ingredients; 8. Patients have been exposed to the study drug within one month before enrollment; 9. Patients who are pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CASA-Q; | — |
Secondary
| Measure | Time frame |
|---|---|
| COPD assessment test;mMRC;CCQ;WBC;CRP;PCT;Classification of sputum cytology;Average treatment days; | — |
Countries
China
Contacts
Public ContactLin Lin
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed