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Accurate Typing and Individualized Prevention and Treatment of Preclinical Rheumatoid Arthritis Based on Citrullinated Protein Mapping

Accurate Typing and Individualized Prevention and Treatment of Preclinical Rheumatoid Arthritis Based on Citrullinated Protein Mapping

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100042998
Enrollment
Unknown
Registered
2021-02-04
Start date
2021-05-01
Completion date
Unknown
Last updated
2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis

Interventions

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Aged >=30 years and <= 55 years(to the date of selecting); 2. ACPAS positive /ACR RA score 6 / ACPAS negative; 3. No previous history of rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, etc.; 4. No disease-modifying antirheumatic drugs (DMARDs, including biological agents) were used; 5. No use of glucocorticoids; 6. Those who did not participate in any drug trial within 3 months before inclusion; 7. Understand the whole process of the study, participate voluntarily and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant women, women preparing to be pregnant or lactating; 2. Chronic diarrhea or peptic ulcer history in the past 1 year; 3. Have mental disorders, a history of alcohol abuse, drug or other substance abuse; 4. Joint symptoms are caused by other known causes (including but not limited to osteoarthritis, gout, infection, etc.); 5. patients with malignant tumor; 6. Allergic to test drugs or use contraindications; 7. There are other conditions that researchers consider to be not appropriate in the clinical trial.

Design outcomes

Primary

MeasureTime frame
The citrullinate protein site;

Secondary

MeasureTime frame
clinical data;

Countries

China

Contacts

Public ContactYi Zhao

West China School of Medicine, Sichuan University

zhao.y1977@163.com+86 18980605760

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026