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Prospective nested case-controlled trials on early-diagnosis of adhesive small bowel obstruction based on multi-dimensional model (ASBO)

Prospective nested case-controlled trials on early-diagnosis of adhesive small bowel obstruction based on multi-dimensional model (ASBO)

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042990
Enrollment
Unknown
Registered
2021-02-03
Start date
2021-06-01
Completion date
Unknown
Last updated
2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adhesive small bowel obstruction

Interventions

Conservative treatment group:Drugs, nasal bowel decompression tube
Surgical treatment group:Laparotomy or laparoscopic surgery

Sponsors

Union Hospital Affiliated to Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Subjects aged 18 - 75 years; 2. Patients with previous history of abdominal and pelvic surgery and radiotherapy; 3. Patients with obvious obstruction symptoms, including 'pain, vomiting, distension, closure', etc.; 4. Complete abdominal CT (or enhanced CT) imaging examination after admission, and diagnose the patients with small intestinal obstruction; 5. Patients with ECoG score 0 / 1 before operation; 6. Patients with preoperative ASA score I-III; 7. Patients and family members who can understand the study protocol and are willing to participate in the study shall provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with severe mental illness; 3. Patients with extensive abdominal metastasis confirmed by imaging or pathology; 4. After admission, the whole abdominal CT (or enhanced CT) imaging examination was completed, and the patients diagnosed with large bowel obstruction (cases; 2; Colorectal cancer, fecal calculus, long bowel and / or volvulus, etc.); 5. Patients with small intestinal obstruction not caused by abdominal adhesion confirmed by intraoperative exploration or pathology are caused by other causes, such as incarcerated hernia, obstructive lesions (malignant and benign), and some rare causes of intestinal obstruction, such as calculus, inflammatory bowel disease and volvulus; 6. Patients with unstable angina or myocardial infarction within 6 months; 7. Patients with history of cerebral infarction or cerebral hemorrhage within 6 months; 8. Patients with a history of continuous systemic corticosteroid therapy within 1 month.

Design outcomes

Primary

MeasureTime frame
3-year bowel obstruction recurrence rate;

Secondary

MeasureTime frame
Morbidity and mortality rates;3-year overall survival rate;Length of bowel resection;Pattern of adhesive small bowel obstruction;Postoperative recovery course;Intraoperative situation;Postoperative nutritional status and quality of life;Inflammatory and immune response;

Countries

China

Contacts

Public ContactLin Bingqiang

Union Hospital Affiliated to Fujian Medical University

lbqdog2006@163.com+86 13365910838

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026