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Local radiotherapy followed by chemotherapy combined with immunotherapy for oligometastatic esophageal carcinoma

Local radiotherapy followed by chemotherapy combined with immunotherapy for oligometastatic esophageal carcinoma

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042989
Enrollment
Unknown
Registered
2021-02-03
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Single arm :Stereotactic radiotherapy

Sponsors

Mianyang Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with esophageal cancer confirmed by histology or cytology; 2. Patients with less than five metastatic lesions; 3. All metastatic lesions can be treated with stereotactic radiotherapy, and the size of lesions can be measured by RECIST version 1.1; 4. Subjects with ECoG score of 0-2; 5. Subjects aged <= 80 years; 6. Patients whose liver function, kidney function and blood routine meet the treatment standard; 7. The patients who signed the formal informed consent for treatment voluntarily participated in this experiment.

Exclusion criteria

Exclusion criteria: 1. Patients who have received immunotherapy in the past; 2. Patients with other malignant tumors; 3. Patients with severe autoimmune diseases such as immune myocarditis and immune pneumonia; 4. Patients who can not understand the trial requirements, or may not comply with the trial requirements.

Design outcomes

Primary

MeasureTime frame
Progression-free survival;

Secondary

MeasureTime frame
Overall survival;

Countries

China

Contacts

Public ContactLidan Geng

Mianyang Central Hospital

979018189@qq.com+86 15775854750

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026