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The effect and mechanism of Transcutaneous Auricular Vagus Nerve Stimulation on complex regional pain syndrome post stroke

The effect and mechanism of Transcutaneous Auricular Vagus Nerve Stimulation on complex regional pain syndrome post stroke

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042987
Enrollment
Unknown
Registered
2021-02-03
Start date
2021-02-01
Completion date
Unknown
Last updated
2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CRPS post stroke

Interventions

TaVNS Group:Transcutaneous Auricular Vagus Nerve Stimulation +comprehensive rehabilitation training
Contrast Group:comprehensive rehabilitation training

Sponsors

Zhejiang Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients in non acute phase 2 weeks after stroke onset; 2. Subjects in the acute phase of CRPS after stroke; 3. The patient's vital signs are stable and conscious; 4. Patients aged 35-75 years; 5. Subjects with first onset.

Exclusion criteria

Exclusion criteria: 1. Patients with brain injury caused by operation, trauma, brain trauma, brain tumor, etc; 2. Patients with serious heart, liver, lung, kidney and other important organ diseases; 3. Patients with a history of drug abuse, long-term alcoholism, dementia or related diseases (such as Parkinson's disease, vascular dementia, etc.); 4. Patients with rheumatism, rheumatoid arthritis and inflammation around shoulder joint; 5. Patients with brain stem, subarachnoid hemorrhage or lacunar infarction.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Assessment- upper extremity;Levels of inflammatory factors;Functional magnetic resonance imaging of brain;

Secondary

MeasureTime frame
Numerical Rating Scale;

Countries

China

Contacts

Public ContactXiaofeng Zhang

Zhejiang Provincial People's Hospital

zhangxiaofengmengn@163.com+86 15957100044

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026