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Clinical study on the relationship between the dose of alfentanil and the occurrence of cough during anesthesia outside the operating room

Clinical study on the relationship between the dose of alfentanil and the occurrence of cough during anesthesia outside the operating room

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042984
Enrollment
Unknown
Registered
2021-02-03
Start date
2021-02-02
Completion date
Unknown
Last updated
2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alfentanil-induced cough outside the operating room

Interventions

Sponsors

Yichang Central People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Subjects aged 18-65 years old; 2. Subjects of ASA grade I to II; 3. Subjects scheduled for hysteroscopy and other short operations (general anesthesia with intravenous or laryngeal mask implantation); 4. Subjects with estimated anesthesia operation time <= 90 min.

Exclusion criteria

Exclusion criteria: 1. Body mass index (BMI): BMI >= 28 kg / m2 or = 28KG; 2. Patients with history of opioid allergy; 3. Patients who used sedatives, antiemetics and anti pruritus drugs 24 hours before operation; 4. Patients with body temperature higher than 38 ? within 24 hours before operation or with symptoms of acute upper respiratory tract infection; 5. Patients with history of bronchial asthma.

Design outcomes

Primary

MeasureTime frame
Cough frequency within 3 minutes after administration;Time of cough reaction after administration;Number of people requiring assisted breathing;

Countries

China

Contacts

Public ContactGong Yuan

Yichang Central People's Hospital

gy-yc@163.com+86 13986746821

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026