focal onset epilepsy
Conditions
Interventions
Transcranial direct current stimulation and repetitive transcranial magnetic stimulation group:Transcranial direct current stimulation and repetitive transcranial magnetic stimulation
Sponsors
Xuanwu Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
14 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Aged 14-60 years; 2.Diagnosis of focal onset epilepsy, seizures form focal origins of aware or impaired awareness, either with or without progress for bilateral tonic-clonic seizure, including automatisms, hyperkinetic, autonomic, behavior arrest, cognitive, emotional, sensory and the focal onset of atonic, clonic, epileptic spasms, myoclonic, tonic; 3.History of epilepsy >= 2 years, regular medication >= 1 years; 4.Seizure frequency >= 1 per week recently 3 months, either with or without secondary generalization; 5.Daily dose of the concomitant antiepileptic drugs (AEDs) were unchanged for the baseline period(4 weeks) and throughout the whole study duration (31 weeks). If there is no obviously clinical need, do not change the drug regimen, and do not increase the traditional Chinese medicine treatment.
Exclusion criteria
Exclusion criteria: 1.Epilepsy nidus cannot be clearly located or the epilepsy niduses are two or more; 2.Previous or existing psychogenic seizures; 3.Epileptic status >= 1 time occurred within 6 months before screening; 4.Evidence of progressive brain disorders or systemic diseases; 5.Alcohol abuse or drug addiction, pregnancy, skull defects, or implantation of other electrical medical devices.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seizures frequency; | — |
Secondary
| Measure | Time frame |
|---|---|
| EEG recordings;Mean time of first onset of epilepsy after stimulation therapy;The percentage of people whose seizures disappear; | — |
Countries
China
Contacts
Public ContactYuping Wang
Xuanwu Hospital, Capital Medical University
Outcome results
None listed