melasma
Conditions
Interventions
Group A:hydroquinone+picosecond laser
Group B:microneedle+picosecond laser
Sponsors
Beijing Friendship Hospital affiliated to Capital Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Female patients aged 18-60 years; 2. The patients with melasma and symmetrical facial rash were diagnosed; 3. The facial skin was basically intact without obvious inflammation, ulceration and exudation; 4. Those who have not received any treatment (including laser, oral medication) in the past 6 months; 5. No history of sun exposure in recent 3 months; 6. Good compliance and regular follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiovascular and cerebrovascular diseases, liver and kidney diseases, hematopoietic system diseases, mental diseases and immunodeficiency diseases; 2. Pregnant or lactating women; 3. Allergic to the test drug and its components; 4. Researchers participating in other clinical trials; 5. The researcher thinks that it is not suitable to participate in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melasma area severity index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Reflectance confocal microscopy; | — |
Countries
China
Contacts
Public ContactZhuo Fenglin
Beijing Friendship Hospital affiliated to Capital Medical University
Outcome results
None listed