Chronic atrophic gastritis ,gastric cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age of 18-75 years old, regardless of gender; 2) the result of electronic gastroscopy was suspected of atrophic gastritis or gastric cancer; 3) good compliance and can cooperate to complete the entire clinical trial; 4) the subject volunteered to participate in the trial, and the subject or its legal agent signed the informed consent.
Exclusion criteria
Exclusion criteria: 1) Active bleeding at the observation site; 2) patient with acute severe throat disease who cannot allow insertion of endoscope; 3) patient with organ stenosis who were difficult to complete endoscopy; 4) patient suspected of shock, esophageal and gastrointestinal perforation; 5) acute phase of corrosive esophageal injury; 6) patients who were taking or had a history of taking anti-thrombotic drugs; 7) severe heart disease such as severe arrhythmia, especially slow ventricular rate, acute myocardial infarction and severe heart failure; 8) severe lung diseases such as bronchial asthmatic attack, cardiopulmonary failure, etc.; 9) patient with severe complications or advanced malignant tumors; 10) patient who cannot tolerate general anesthesia; 11) pregnant women and lactating women; 12) allergy to sodium fluorescein solution; 13) in any case, if the researcher thought the patient was not suitable for this test (such as the patient did not want to avoid other tests, the patient was unwilling to accept the research plan, the expected value of patient was unrealistic or patient had obvious emotional problems).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| confocal laser endomicroscopy imaging ;SEN, SPE, ACC, AUC of ROC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Biopsy; | — |
Countries
China
Contacts
Wuhan Union Hospital