ERCP
Conditions
Interventions
R Group:Remimazolam Tosilate
F Group :Midazolam combined with etomidate
Sponsors
Second Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Patients scheduled for therapeutic ERCP under total intravenous anesthesia; (2) They were 60-89 years old; (3) ASA grade II, III; (4) Sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Severe cardiovascular disease (such as preoperative blood pressure >= 180 / 110mmhg), malignant arrhythmia, myocardial infarction, nhya heart function grade >= III, severe valve insufficiency within 3 months); (2) Severe bradycardia (< 50 beats / min) and severe hypotension (map < 60mmhg) were found; (3) Severe nervous system diseases (such as Parkinson's disease, epilepsy, stroke, intracerebral hemorrhage, etc.) not effectively controlled; (4) Difficult airway and severe respiratory diseases (such as difficult airway, osaha, acute exacerbation of chronic lung disease, asthma exacerbation, SpO2 <= 90% before operation, etc.); (5) A history of long-term or suspected abuse of psychotropic drugs, drug use, and alcohol abuse was identified or suspected; (6) Allergic to narcotic sedative analgesics; (7) Communication barriers, difficult to cooperate; (8) preoperative 6h and fasting or / or 2H * gastric emptying disorders had reached the time of fasting, but gastric retention was still visible under ultrasound.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Basic vital signs at each observation time point;Operation time, recovery time, VAS score, satisfaction and other related indicators of recovery period;The dosage of drugs, the success rate of sedation and other sedation related indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery of orientation and muscle strength;Safety index evaluation; | — |
Countries
China
Contacts
Public ContactJin-Gui Gao
The Second Hospital of Hebei Medical University
Outcome results
None listed