Mechanism of breast cancer exosomes regulating fibroblast secretion function and participating in the of pre-metastasis niche establishment

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100042937

Enrollment

Unknown

Registered

2021-02-01

Start date

2021-02-01

Completion date

Unknown

Last updated

2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

Breast cancer patients (no metastasis):None

Breast cancer patients (metastasis):None

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Female breast cancer patients confirmed by pathology; 2) Karnofsky score >= 70 and estimated survival time >= 3 months.

Exclusion criteria

Exclusion criteria: 1) The researchers believe that the subjects have serious systemic diseases and are not suitable to participate in this clinical study; 2) People with mental disorders or poor compliance.

Design outcomes

Primary

Measure	Time frame
exosomes miR-122 expression level of blood;Expression level of FSP-1 in breast cancer tissue specimens;Expression level of a-SMA in breast cancer tissue specimens;Expression level of ARF1 in breast cancer tissue specimens;Expression level of ARAP1 in breast cancer tissue specimens;	—

Countries

China

Contacts

Public ContactXinmei Kang

Department of Oncology, Xiang'an Hospital of Xiamen University

kangxm28@xmu.edu.cn+86 13720879248

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026