The effects of two kinds of corneal refractive surgery (FS-LASIK and Trans-PRK) on tear film stability and ocular surface related indexes in patients with medium and low degree myopia

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100042913

Enrollment

Unknown

Registered

2021-01-31

Start date

2021-01-31

Completion date

Unknown

Last updated

2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractive surgery

Interventions

FS-LASIK surgery:FS-LASIK surgery

Trans-PRK surgery:Trans-PRK surgery

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 years or above, regardless of gender and nationality; 2. Those patients who meet the indications of corneal refractive surgery and have no surgical contraindications; 3. Patients who stop wearing contact lenses for more than one month; 4. Patients who signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with conjunctival and corneal active inflammatory diseases and other conjunctival and corneal diseases that affect tear film; 2. Lacrimal organ disease; 3. Patients who use drugs that affect tear film secretion and tear film stability; 4. Patients with systemic connective tissue disease were excluded; 5. Patients with corneal flap accident during LASIK were excluded.

Design outcomes

Primary

Measure	Time frame
tear film lipid thickness level;tear film break up time;tear film break up time;TMH;corneal sensitivity;	—

Countries

China

Contacts

Public ContactZhao Shaozhen

Eye Hospital of Tianjin Medical University

zhaosz1997@sina.com+86 13802036813

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026