????????? ????????? Primary microvascular angina
Conditions
Interventions
Sponsors
Hangzhou Red Cross Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: PMVA diagnostic criteria: (1) exertional angina pectoris at least half a year, chest pain lasting more than 10 minutes, nitroglycerin treatment effect is poor. (2) There was at least one typical ST segment ischemic depression >= 0.01mm in ECG or Holter. (3) Exercise treadmill test was positive (ST segment ischemic depression >= 0.01mm). (4) Echocardiography showed no segmental wall motion abnormality and normal left ventricular function. (5) Coronary angiography showed that the lumen was normal or close to normal (angiography results showed that the subepicardial coronary artery wall was normal or irregular, and the degree of stenosis was less than 20%), there was no spontaneous coronary artery spasm, and TIMI blood flow was 1-2 grade. Diagnostic criteria of traditional Chinese Medicine: syndrome of phlegm-heat stasis and obstruction, main syndrome: chest tightness, such as suffocation and pain, burning sensation; secondary syndrome: dry and upset mouth; dry or bitter mouth, do not want to drink or drink does not quench thirst; obesity, phlegm yellow sticky, face hot; greasy fur, or with little body fluid cracks or greasy fur; tongue purple dark or see ecchymosis or red, pulse slippery number or knot generation, or string, or astringent. 1 item of main syndrome and 2-3 items of secondary syndrome can be selected. Inclusion criteria: patients aged 18-75 years who met the diagnostic criteria of PMVA.
Exclusion criteria
Exclusion criteria: (1) Organic heart disease: coronary atherosclerotic heart disease, coronary artery spasm, coronary artery muscle bridge, all kinds of cardiomyopathy, congenital heart disease, valvular heart disease, pulmonary heart disease, etc.; (2) myocardial injury: myocarditis, systemic disease combined with myocardial injury, etc.; (3) patients with hypertension, hyperlipidemia, diabetes mellitus; (4) arrhythmia requiring drug control (5) complete left bundle branch block, degree II and III atrioventricular block, sick sinus syndrome; (6) severe congestive heart failure; (7) malignant tumor; (8) lung, esophagus, aortic dissection and other diseases that can cause chest pain; (9) severe liver and kidney dysfunction; (10) severe trauma patients; (11) endocrine system diseases; (12) anemia and other blood diseases Systemic diseases; (13) peripheral vascular diseases; (14) pregnant and lactating women; (15) patients treated with antibiotics or hormones within 3 months; (16) patients allergic to traditional Chinese medicine preparations including Coptis, gardenia, Fructus aurantii Immaturus, Zhuru, pinellia, Pericarpium Citri Reticulatae, Poria cocos, Salvia miltiorrhiza, Curcuma and licorice; (17) patients unable to persist in treatment or poor treatment compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| von Willebrand factor, vWF;homocysteine, Hcy; | — |
Countries
China
Contacts
Public ContactHuang Qi
Hangzhou Red Cross Hospital
Outcome results
None listed