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Clinical study of gastric microbiota change subsequent to TIPS in liver cirrhosis patients with portal hypertension gastropathy

Clinical study of gastric microbiota change subsequent to TIPS in liver cirrhosis patients with portal hypertension gastropathy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100042882
Enrollment
Unknown
Registered
2021-01-31
Start date
2021-02-01
Completion date
Unknown
Last updated
2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cirrhosis

Interventions

case series:Nil

Sponsors

Department of Gastroenterology,Army Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 yearsno limitation of gender; 2. Diagnosed with liver cirrhosis and intended for first TIPS; 3. No serious complications; 4. Consented to the following tests: 1) Hematological tests; 2) Gastroscopic examination and gastric mucosa biopsy (gastric fundus, gastric body, gastric antrum); 3) Ultrasonic examination; 5. Able to receive subsequent?visit and follow-up examination on time; 6. Willing to participate in the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Unwilling to undergo gastroscopy or contraindication; 2. Antibiotics, probiotics and PPI taken within 1 month before enrollment; 3. Previous treatments with surgical shunt; 4. History of liver or stomach surgery; 5. Subjective unwillingness to continue the clinical study; 6. Severe major organ failure (heart, lung, kidney, etc.), severe infection and non-hepatic malignancies; 7. Any medical or non-medical condition that the researcher considers unfit to participate in.

Design outcomes

Primary

MeasureTime frame
Gastric microbiota;

Countries

China

Contacts

Public ContactChen Dongfeng

Department of Gastroenterology, Army Medical Center,

chendf1981@126.com+86 23-58729147

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026