Hepatocellular carcinoma
Conditions
Interventions
Sponsors
Shulan (Hangzhou) hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients who signed informed consent voluntarily; 2. Subjects aged from 18 to 70 years; 3. Recipients of liver transplantation with liver cancer who have received organ donation and living donor after the citizen's death, and who have exceeded Milan standard, have no major vascular invasion except portal vein branch, and have no distant metastasis; 4. The subjects confirmed by histopathology as hepatocellular carcinoma.
Exclusion criteria
Exclusion criteria: 1. Patients with multiple organ transplantation; 2. Patients with high sensitivity to sirolimus or its derivatives have been identified; 3. Patients with Refractory Hyperlipidemia (triglyceride >= 400 mg / dl (>= 4.6 mmol / L) and total cholesterol >= 300 mg / dl (>= 7.8 mmol / L) still exist under the best treatment scheme; 4. Patients with signs of systemic infection or important local active infection; 5. HIV positive patients; 6. Patients with platelet < 35 x 10^9 / L and leukocyte < 1.5 x 10^9 / L; 7. Patients with urinary albumin + +; A woman who is preparing for pregnancy or lactation; 9. Patients with a history of non hepatocellular carcinoma (except basal cell carcinoma and squamous cell carcinoma) in the previous 5 years were enrolled; 10. Patients who are difficult to cooperate with the implementation of the research program and follow-up plan in terms of psychological, family, social or geographical conditions (such as individuals who cannot freely sign informed consent).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor-related death;incidence of allograft rejection;incidence of graft loss;alterations in renal function; | — |
Countries
China
Contacts
Public ContactShusen Zheng
Shulan (Hangzhou) hospital
Outcome results
None listed