Complex abdominal wall defect
Conditions
Interventions
experimental group:Whether to use 3D reconstruction techniques for preoperative planning
contral group:3D reconstruction was not performed preoperatively
Sponsors
The ninth People's Hospital affiliated to Shanghai Jiao Tong University Medical College
Eligibility
Sex/Gender
Male
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Informed consent was signed by the subject or his legal representative. 2. Subjects aged 18-75 years (including 18 and 75 years), regardless of gender. 3. Patients who met the diagnostic criteria of Chinese expert consensus on repair and reconstruction of abdominal wall defects (2019 Edition). (1) The size and location of abdominal wall defect: huge abdominal wall defect (defect width >= 10cm), abdominal wall defect with loss of domain (LOD), abdominal wall defect in special parts such as suprapubic and subcostal. (2) The condition of abdominal wall soft tissue: with contamination or infection, abdominal wall tumor after extended resection, severe trauma, multiple operations, skin grafting, ulcer or refractory wound, and abdominal wall defect beside stoma or fistula. (3) General condition and past disease history of the patient: accompanied by various risk factors, such as obesity, diabetes, chronic obstructive pulmonary disease, large amount of ascites, use of steroids, poor nutritional status and other diseases, with a history of incision dehiscence, and recurrent abdominal wall defects repaired by patch or tissue structure separation technology. (4) Clinical condition: open abdominal cavity, or with incarceration and strangulation of intestinal tube, intestinal resection, patch removal and multiple abdominal wall defects should be performed at the same time. 4. Patients who agree to 3D visualization and 3D printing preoperative planning.
Exclusion criteria
Exclusion criteria: 1. Patients who participated in other clinical trials within 3 months before the start of this trial; 2. Pregnant, lactating women and patients planning to be pregnant; 3. Patients undergoing radiotherapy or chemotherapy; 4. Cardiovascular and cerebrovascular diseases were not controlled, NYHA cardiac function grade II or above 5. Patients with severe endocrine and metabolic diseases, systemic immune diseases, blood and respiratory diseases judged by researchers are not suitable for this trial; 6. Uncontrolled infection in the whole body; 7. Patients with liver disease or liver injury (ALT and AST exceed 2 times of the upper limit of normal value); 8. Patients with severe renal injury or renal failure (serum creatinine is more than 2 times of the upper limit of normal value); 9. Patients who cannot complete the follow-up regularly. 10. Alcoholics, drug addicts or other drug addicts have a tendency; 11. Patients who could not tolerate enhanced CT examination; 12. HIV antibody screening positive patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| recovery rate;VAS score; | — |
Countries
China
Contacts
Public ContactYan Gu
The Ninth People's Hospital Affiliated to Medical College of Shanghai Jiaotong University
Outcome results
None listed