shock
Conditions
Interventions
Experimental group:After endotracheal intubation for 5 minutes, it begins to infuse phenylephrine of 0.2 µg/kg/min for 5 minutes, and then 5ml/kg ideal body weight of Sodium Lactate Ringer's Injectio
control group:After endotracheal intubation for 5 minutes, it begins to infuse saline solution at the corresponding rate with phenylephrine of 0.2 µg/kg/min for 5 minutes, and then 5ml/kg ideal body w
Sponsors
Department of Anesthesiology, Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who have selective operation under general anesthesia with mechanical ventilation for more than 2 hours; 2. Age 65 and above, gender is not limited; 3. The ASA class I, II, III; 4. Heart function grade of NYHA I, II, systolic blood pressure < 180 mmHg, diastolic pressure < 110 mmHg; 5. 18.5 kg / ? <= BMI < 27.9 kg / ?; 6. Patients who are willing to cooperate with this study, understand and voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Presence of hypertension grade 3 (very high risk), severe arrhythmia, severe heart valve disease, left ventricular ejection fraction < 50%; 2. There are contraindications of central venous catheterization or radial artery catheterization; 3. The patient had a pulmonary infection two weeks before surgery or severe pulmonary disease or a history of lobotomy; 4. Other serious organ dysfunction, such as liver function Child grade C, uremia; 5. For other reasons, the investigator considers it inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| stroke volume index; | — |
Secondary
| Measure | Time frame |
|---|---|
| stroke volume variation;pulse pressure variation; | — |
Countries
China
Contacts
Public ContactHongfei Zhang
Department of Anesthesiology, Zhujiang Hospital of Southern Medical University
Outcome results
None listed