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Ultrasound guided fine needle aspiration cytology combined with immunocytochemistry and detection of miRNA molecular markers to construct a differential diagnosis system for thyroid nodules

Ultrasound guided fine needle aspiration cytology combined with immunocytochemistry and detection of miRNA molecular markers to construct a differential diagnosis system for thyroid nodules

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100042840
Enrollment
Unknown
Registered
2021-01-30
Start date
2021-01-30
Completion date
Unknown
Last updated
2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid nodule

Interventions

Gold Standard:Surgical pathology
Index test:TI-RADS&#32
classification,&#32
BRAF&#32
V600&#32
gene,&#32
Immunocytochemical&#32
molecular&#32
markers&#32
miRNA,&#32
thyroid&#32
nodule&#32
pathology

Sponsors

Department of Endocrinology, Second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Age 18 to 70 years old; (2) Patients with thyroid nodules by ultrasound.

Exclusion criteria

Exclusion criteria: (1) Complicated with other tumors, chronic infections, blood and immune system diseases; (2) Pregnant and lactating women; (3) A history of thyroid cancer surgery; (4) Pure cystic nodules of thyroid.

Design outcomes

Primary

MeasureTime frame
Thyroid Imaging Reporting and Data System;Immunocytochemical molecular markers;BRAF-V600E;miRNA;Thyroid stimulating hormone;Thyroid fine needle puncture cytology report;The pathological report;SEN, SPE, ACC, AUC of ROC;—

Countries

China

Contacts

Public ContactTianrong Pan

The Second Affiliated Hospital of Anhui Medical University

ptr1968@163.com+86 15305609568

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026