Thoracic cancer
Conditions
Interventions
Experimental group: Contains omega-3 fatty acids:Take the test sample three times a day
Placebo group: No omega-3 fatty acids:Take the placebo regularly three times a day
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed as thoracic malignant tumor and in tumor bearing state; 2. Subjects aged from 18 to 80 years old; 3. Patients with NRS 2002 >= 3; 4. Subjects whose oral diet could not meet the target requirement and 60% needed oral nutrition supplement; 5. Patients with good gastrointestinal function; 6. Patients who signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients whose expected survival time is less than 3 months; 2. Patients after radical resection of tumor; 3. Patients with gastrointestinal function, such as acute enteritis, intestinal obstruction, gastrointestinal bleeding, radiation enteritis, ischemic colitis, ulcerative colitis, allergic gastrointestinal syndrome, etc; 4. Patients receiving immunosuppressive therapy or any disease leading to immunosuppression (including hematological malignancies and AIDS); 5. Patients treated with antibiotics for a long time before the trial; 6. Patients with total parenteral nutrition; 7. Pregnant or lactating women; 8. Subjects participating in other clinical trials; 9. Other researchers think it is not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| T cell subsets (CD3, CD4, CD8);Immunoglobulin (IgG, IgA, IgM);Serum CRP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor necrosis factor (TNF-a);Serum albumin;Routine blood;Detection of body composition;physical examination;PG-SGA rating scale;Quality of Life Scale; | — |
Countries
China
Contacts
Public ContactWen Hu
West China Hospital of Sichuan University
Outcome results
None listed