Gastrointestinal hemorrhage
Conditions
Interventions
Trial group:Proton pump inhibition + somatostatin + tranexamic acid therapy
control group:Proton pump inhibition + somatostatin therapy
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed as acute gastrointestinal bleeding by clinical diagnosis; 2. The patients or his family members signed to participate in the study; 3. Patients over 18 years old.
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart, liver and kidney dysfunction; 2. Patients with hemodynamic instability and shock; 3. Identify patients allergic to tranexamic acid or pregnant women with contraindications; 4. Patients taking anticoagulants or aspirin for less than one week; 5. Patients with blood diseases and family history of hemorrhagic diseases; 6. Patients with history of venous thromboembolism, pulmonary embolism, cerebral infarction, coronary heart disease and high risk of thrombosis, including atrial fibrillation, cardiac pacemaker and stent implantation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| thromboelastography; | — |
Countries
China
Contacts
Public ContactNie Hu
Emergency department of West China Hospital of Sichuan University
Outcome results
None listed