Gastric cancer
Conditions
Interventions
A Group:total laparoscopic transthoracic approach overlap reconstruction
B Group:total thora-laparoscopic combined Sweet esophagectomy
C Group:total thora-laparoscopic combined Ivor - Lewis esophagectomy
Sponsors
Affiliated Xijing Hospital of Airforce Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed as Siewert type II adenocarcinoma of esophagogastric junction by endoscopy or histology; 2. The tumor met the resectable condition: ct1-t3, no distant metastasis (N0-N1 and M0); 3. Patients who underwent total laparoscopic thoracic approach overlap reconstruction or total thoracoscopic combined with sweet or total thoracoscopic combined with Ivor Lewis; 4. Patients who have not received chemotherapy or radiotherapy in the past; 5. Patients with ECoG <= 2; 6. (American Society of anesthesiologists) patients with ASA < 3; 7. Subjects with nrs2002 nutritional score <= 2; 8. Subjects who signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients over 75 years old; 2. Those patients with enlarged lymph nodes in the upper mediastinum over 5 mm; 3. Patients with other malignant tumor diseases; 4. Patients with a history of gastroesophageal surgery; 5. Patients who have received neoadjuvant chemotherapy or radiotherapy in the past; 6. Patients with other serious organ dysfunction; 7. Patients with Karnofsky index lower than 80.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| time of operation;postoperative hospitalization duration;Incidence of postoperative reflux within 1 year;The recurrence and metastasis rate 1 year after operation;One-year survival rate after surgery;Incidence of cardiopulmonary complications;Incidence of postoperative bleeding; | — |
Primary
| Measure | Time frame |
|---|---|
| the positive rate of resection margin residual cancer;Average number of dissected lymph nodes;Time of first exhaust and defecation after operation;anastomotic leakage;postoperative infection; | — |
Countries
China
Contacts
Public ContactGang Ji
Affiliated Xijing Hospital of Airforce Military Medical University
Outcome results
None listed