A Randomized Controlled Study for N-back Training Combined with tDCS in the Treatment of Executive dysfunction after stroke

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100042798

Enrollment

Unknown

Registered

2021-01-28

Start date

2021-02-01

Completion date

Unknown

Last updated

2021-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Executive dysfunction after stroke

Interventions

stroke group:None

n-back+tDCS group:n-back+tDCS

control group:Conventional treatment

Healthy control group:none

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Experiment one: Stroke patients including hemorrhagic or ischemic; all cases were confirmed by head CT or MRI examination for the first time, in line with the criteria for stroke diagnosis, all cases of clear diagnosis, vital signs stability (body temperature, breathing, pulse, blood pressure ), Neurological signs no longer progress after 2 weeks. All participants had normal or corrected-to-normal vision, and no hearing impairment. They could sit in chair more than 30 minutes ,and also can press a computer keyboard and complete the scales using at lest one hand. MOCA-B >= 19. Experiment two: Stroke patients including hemorrhagic or ischemic; Aged 50-80 years; all cases were confirmed as stroke of internal carotid artery system by head CT or MRI examination for the first time, in line with the criteria for stroke diagnosis, all cases of clear diagnosis, vital signs stability (body temperature, breathing, pulse, blood pressure), Neurological signs no longer progress after 2 weeks. All participants had normal or corrected-to-normal vision, and no hearing impairment. They could sit in chair more than 30 minutes ,and also can press a computer keyboard and complete the scales using at lest one hand. MOCA-B >= 19; STTA >= 1.0SD,and STTB>= 1.0SD.

Exclusion criteria

Exclusion criteria: Experiment oneknown intolerance of tests: unstable diseasenot cooperate with tests; neglect hemianopiasevere aphasiasevere psychiatric symptoms; years of education <= 5 years. Experiment twoknown intolerance of tests: unstable diseasenot cooperate with test; sneglect hemianopiasevere aphasiasevere psychiatric symptoms; Intracranial metal implants; Brain stimulator; Accepted Ventriculo-abdominal Shunt; Local skin lesions or inflammatory hyperalgesia; Uncontrolled epilepsy; Family history of dementia patients; years of education <=5 years.

Design outcomes

Primary

Measure	Time frame
The Shape Trail Test;	—

Secondary

Measure	Time frame
n-back( accuracy rate and reaction time);	—

Countries

China

Contacts

Public ContactXiuzhen Liu

Xuanwu Hospital, Capital Medical University

tongxingyouyu@126.com+86 13311599279

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026