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To assess the effect of extensive renal artery dissection during robotic-assisted partial nephrectomy on blood pressure of patients with poorly controlled hypertension

A prospective randomized controlled study to assess the effect of extensive renal artery dissection during robotic-assisted partial nephrectomy on blood pressure of patients with poorly controlled hypertension

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042790
Enrollment
Unknown
Registered
2021-01-28
Start date
2021-04-01
Completion date
Unknown
Last updated
2021-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypertension

Interventions

Intervention group:extensive renal artery dissection
control group:Nil

Sponsors

Nanjing Drum Tower Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Aged >= 18 years old and = 150mmHg or diastolic blood pressure >= 90mmHg; or an average 24-hour ambulatory blood pressure monitoring contraction Pressure >= 135mmHg; b) After taking three or more antihypertensive drugs for more than 4 weeks (including a diuretic), blood pressure is still poorly controlled, blood pressure in the office for 3 times (sitting position), systolic blood pressure >= 140mmHg or diastolic blood pressure >= 90mmHg; or Average 24-hour ambulatory blood pressure monitoring systolic blood pressure >= 130mmHg; c) Definitely diagnosed as renal hypertension or essential hypertension; 5) The subject voluntarily participates, and the subject must sign an informed consent form (ICF), indicating that he understands the purpose and required procedures of the study, and is willing to participate in the study. Subjects must be willing and abide by the prohibitions and restrictions specified in the research protocol.

Exclusion criteria

Exclusion criteria: Meet any of the following: 1) Bilateral renal tumors; 2) Kidney tumor > 7cm; 3) Severe renal atherosclerosis; 4) End-stage renal disease; 5) Secondary hypertension; 6) Other situations where the researcher thinks it is inappropriate to participate in this research.

Design outcomes

Primary

MeasureTime frame
blood pressure;heart rate;

Secondary

MeasureTime frame
Renin;Angiotensin;Aldosterone;

Countries

China

Contacts

Public ContactHongqian Guo

Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School

gymwpi@126.com+86 13605171690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026