heart failure
Conditions
Interventions
control group:None
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Man or woman, 18 ~ 75 years, BMI18-30 kg/m2, LVEF < 0.40, NYHA I ~ IV; 2. angiotensin converting enzyme inhibitors, beta-blockers drugs such as the same or similar, at least 2 weeks, with stable drug treatment dose stable up to 2 weeks; 3. Echocardiographic examination: LVEF < 40%.
Exclusion criteria
Exclusion criteria: 1. Unstable angina pectoris; 2. Systolic blood pressure >200mmHg at rest or diastolic blood pressure >110mmHg at rest; 3. Postural blood pressure decreased > 20mmHg, accompanied by symptoms; 4. Severe aortic stenosis (peak systolic pressure gradient > 50mmHg, aortic valve orifice area 120 beats/min); III degrees AVB (not installed pacemakers); 7. Active pericarditis or myocarditis; 8. Recent history of embolism;Thrombophlebitis; 9. At rest, the ECG showed ST segment shift >2mm. 10. Uncontrolled diabetes (resting blood glucose >400mg/ dL); 11. The presence of physical movement disorders; 12. Other metabolic problems, such as acute thyroiditis, hypokalemia, hyperkalemia, or hypovolemia; 13. Anemia, liver and kidney insufficiency, chronic obstructive pulmonary disease; 14. Mental disorder or inability to sign informed consent; 15. Congenital heart disease, rheumatic valvular disease, hypertrophic obstructive cardiomyopathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-minute walking test;anaerobic threshold; | — |
Countries
China
Contacts
Public ContactShen YuQin
Shanghai Tongji Hospital
Outcome results
None listed