diabetic peripheral neuropathy
Conditions
Interventions
Sponsors
Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. All potential patients will be assessed for trial eligibility by a clinician; 2. Have diagnostic type 2 diabetes with diabetic peripheral neuropathy: (1) having a history of type 2 diabetes; (2) having diabetic peripheral neuropathy upon being or after being diagnosed with type 2 diabetes; (3) in patients with clinical symptoms of neuropathy, diabetic peripheral neuropathy is diagnosed in >= 1 of the following 5 tests; in patients without clinical symptoms, diabetic peripheral neuropathy is diagnosed in >= 2 of the following 5 tests: A.abnormal temperature sensation; B.abnormal pressure sensation; C. abnormal vibration sensation; D. abnormal pinprick pain sensation (10g nylon wire examination, reduced or absent sensation in the foot); E. absent ankle reflex. 3. Aged 18 to 80 years; 4. Having an electronic device at home (e.g., a computer or mobile phone): can have access to online Qigong exercise program; 5. Willing and able to regularly attend online Qigong exercise for 3 times/week, 1-1.5 hours/session ; 6. Able to cooperate with requirement of study (including assessments, etc.); 7. Able to do Qigong exercise, and cooperate with the instructor of the online Qigong intervention program; 8. Will not participate in any other clinical trials during the study; 9. Will not practise any other Tai Chi or Qigong exercise during the study.
Exclusion criteria
Exclusion criteria: 1. Other diseases diagnosed by clinicians, including cervical and lumbar disease (e.g., nerve root compression, stenosis, vertebral degeneration), cerebral infarction, Guillain-Barre syndrome, severe arteriovenous vascular diseases (e.g., venous thrombosis, lymphangitis); and peripheral neuropathy caused by drugs (especially chemotherapy)and renal insufficiency; 2. According to the recommendations of the American Academy of Sports Medicine in 2000, it is forbidden to participate in physical activities (e.g., unstable angina, uncontrolled blood pressure > 200/110 mmHg, orthostatic hypotension > 20 mmHg, critical aortic stenosis, uncontrolled atrial or ventricular arrythmia, uncontrolled sinus tachycardia, acute systemic illness or fever, moderate to severe heart failure, 3 degrees AV block, active pericarditis or myocarditis, recent embolism, thrombophlebitis, resting ST segment displacement [>2mm]); 3. A diagnosis of dementia, malignant tumor or life-threatening disease; 4. History of bipolar disorder, schizophrenia and other severe mental diseases including major depressive disorder(except depression symptoms); 5. History of severe hypoglycemia; 6. Pregnant women, lactating women or those who plan to become pregnant in the next 6 months; 7. Practiced Tai Chi or Qigong in the past 3 months; 8. Addicts of alcohol and caffeine; 9. Have planned to move to another city or overseas in the coming 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nerve conduction velocity;Toronto clinical scoring system;Glycated hemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting plasma glucose;Fasting insulin;Insulin resistance;Hemorheology;Laser doppler flowmetry inspection;Nerve growth factor;Inflammatory cytokines(interleukin-1ß, interleukin-6, interleukin-10, tumor necrosis factor alpha and C-reactive protein);Serum cortisol;Height, weight, body mass index;Waist circumference;Blood pressure;The Morse Risk Assessment Scale for Falls;Single leg stance with eyes closed;Timed up and go test;The 30-s Chair stand test;Pittsburgh Sleep Index Scale;Depression Anxiety Stress Scale 21;the Short-Form 36 item health;the Physical Activity Enjoyment Scale;TCM Symptom score; | — |
Countries
China
Contacts
Public ContactLiu Xin
Beijing University of Chinese Medicine
Outcome results
None listed