diagnosis and treatment of gastrointestinal endoscopy
Conditions
Interventions
1:remazolam tosylate
2:remazolam tosylate
Sponsors
The Third Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Aged 18-60 years, regardless of sex. 2)Patients who receive routine gastrointestinal endoscopy. 3) ASA score is I, II or III. 4) 18kg/m2< BMI < 30kg/m2. 5) The operation time of gastrointestinal endoscopy is expected to be no longer than that of 30min. 6) Clearly understand and voluntarily participate in the study, and the informed consent form shall be signed by him.
Exclusion criteria
Exclusion criteria: Patients with any of the following items cannot be enrolled in this study: 1) Complex endoscopic techniques (such as cholangiopancreatography, endoscopic ultrasonography, endoscopic mucosal resection, endoscopic submucosal dissection, transoral endoscopic myotomy, etc.). 2) Patients who are going to undergo endotracheal intubation. 3) Patients with respiratory tract management difficulties (modified Mahalanobis score as IV). 4) There is a history of drug use and / or alcohol abuse in the 2 years before the start of the screening period, that is, drinking more than 2 units of alcohol per day on average. (1 unit = 360 mL beer or 45 mL spirits with 40% alcohol or 150 mL wine). 5) The systolic blood pressure of sitting position during the screening period is less than 90 mmHg. 6) Pregnant or lactating women. 7) Allergic or taboo to benzodiazepines, opioids, lidocaine and their drug components. 8)The liver function the renal function is abnormal. 9) Participated in clinical trials of remazolam tosylate or other drugs as subjects in the past 3 months. 10) The researchers do not think it is appropriate for patients to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation success rate;Sedation induction time ; | — |
Secondary
| Measure | Time frame |
|---|---|
| recovery of Neuro psychiatric function;Sedation and awakening time;Incidence of hypotension;Incidence of respiratory depression during sedation;Incidence of sedative hypotension requiring treatment;Satisfaction score;Departure time; | — |
Countries
China
Contacts
Public ContactWen Ouyang
The Third Xiangya Hospital of Central South University
Outcome results
None listed