Estrogen receptor-positive breast cancer
Conditions
Sponsors
Shanghai Municipal Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Breast cancer patients with previous postoperative histopathological diagnosis and tumor staging between Stage I and III, but not stage IV; 2. The patient is already in the postmenopausal state; 3. Postoperatively, 4. Immunohistochemical patients were ER positive or PR positive and HER2 negative. 5. Patients aged between 45 and 80 years; 6. Physical condition score KPS >= 80, and the expected survival time is more than 1 year. 7. No obvious dysfunction of important organs such as heart, lung, liver and kidney. White blood cells >= 4.0 x 10^9/L; For granulogram count >= 2.0 x 10^9/L, hemoglobin >= 10g/L, total bilirubin <= 30 mol/L, alanine aminotransferase <= 40 u /L, alanine aminotransferase <= 40U/L, creatinine <= 130 mg/dl, urea nitrogen <= 7.14mmol/L; 8. Meet the diagnostic criteria of osteopenia and osteoporosis; 9. Is taking letrozole, anastrozole and exemestane, one of the endocrine drugs; 10. Syndrome differentiation of TCM belongs to liver depression and spleen deficiency syndrome.
Exclusion criteria
Exclusion criteria: 1. Allergic to letrozole, anastrozole and exemestane; 2. The patient has uncontrolled infection or severe medical disease; 3. Those with tumor invasion of the brain and not effectively controlled; 4. Those who fail to use the medicine according to the regulations and the incomplete data affect the judgment of curative effect.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone density;progression-free survival;tumor marker; | — |
Secondary
| Measure | Time frame |
|---|---|
| Immunity;traditional Chinese medicine symptom; | — |
Countries
China
Contacts
Public ContactZhu Weikang
Shanghai Municipal Hospital of Traditional Chinese Medicine
Outcome results
None listed