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Comparison of Positive pressure and negative pressure tracheal extubation after mechanical ventilation in ICU patients

Comparison of Positive pressure tracheal extubation and negative pressure after mechanical ventilation in ICU patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042632
Enrollment
Unknown
Registered
2021-01-24
Start date
2020-01-01
Completion date
Unknown
Last updated
2021-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endotracheal intubation and extubation after mechanical ventilation

Interventions

Positive pressure tracheal extubation Group:Disconnect the ventilator, close the breathing valve of the simple breathing apparatus, and use the simple aspirator to give positive pressure ventilation.
negative pressure tracheal extubation Group:Disconnect the ventilator, insert the suction tube into the endotracheal tube across the distal opening, and perform endotracheal negative pressure suction

Sponsors

Nanjing Jiangbei People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients receiving mechanical ventilation via otracheal intubation, who get better after treatment, reach the indications of withdrawal and extubation, and pass the SBT test and the air bag leakage test negative.

Exclusion criteria

Exclusion criteria: 1. Patients with severe lung disease; 2. Patients with severe nervous system dysfunction; 3. Obesity, BMI > 40; 4. Vocal cord paralysis; 5. Myasthenia gravis; 6. Pregnancy.

Design outcomes

Primary

MeasureTime frame
arterial blood gas analysis;BP;heart rate;respiratory rate;oxygen saturation;bucking;airway hyperresponsiveness;

Countries

China

Contacts

Public ContactShangxiang Liu

Nanjing Jiangbei People's Hospital

liu18.00@163.com+86 13914468265

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026