Evaluation of neurological function in DOC patients by music rhythmic paced TMS stimulation induced slow wave oscillation

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100042631

Enrollment

Unknown

Registered

2021-01-24

Start date

2020-01-15

Completion date

Unknown

Last updated

2021-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disorder of consciousness

Interventions

Gold Standard:CRS-R scale

Index test:EEG

Eligibility

Sex/Gender

All

Age

20 Years to 54 Years

Inclusion criteria

Inclusion criteria: 1. Between 20 and 52 years old; 2. In stable condition; 3. Mentally stable; 4. Be able to complete the measurement of CRS-R scale under guidance.

Exclusion criteria

Exclusion criteria: 1. Hearing impairment; 2. Have high music literacy, or have been engaged in music related work; 3. Once took psychoactive drugs; 4. Have received transcranial magnetic stimulation or audiotherapy; 5. There are metal foreign bodies in the head; 6. Wear a pacemaker; 7. Wear cochlear implant; 8. Symptoms of intracranial hypertension diagnosed within 1 month; 9. History of epilepsy or family history of epilepsy; 10. Serious heart disease or recent heart disease.

Design outcomes

Primary

Measure	Time frame
EEG;	—

Secondary

Measure	Time frame
ECG;Respiration rate;	—

Countries

China

Contacts

Public ContactMiaolin Chen

Shenzhen Second People's Hospital

13423803536@163.com+86 13423803536

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026