Effect of ropivacaine combined with lidocaine or dexmedetomidine on phrenic nerve palsy after interscalene brachial plexus block

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100042618

Enrollment

Unknown

Registered

2021-01-24

Start date

2021-02-19

Completion date

Unknown

Last updated

2021-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anesthesia

Interventions

experimental group A:Local anesthetics use 4% ropivacaine 20ml

experimental group B:Local anesthetics were 4% ropivacaine + 1% lidocaine 20ml

experimental group C:Local anesthetics were 4% lidocaine + 1 µ g / kg dexmedetomidine 20ml

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Patients with right upper arm elective surgery; (2) ASA grade I - II; (3) They were 18-65 years old; (4) BMI ranged from 18 to 28, and there was no significant abnormality in cardiopulmonary function.

Exclusion criteria

Exclusion criteria: Arrhythmia; respiratory diseases; injection site infection; severe hepatic and renal insufficiency; coagulation dysfunction; upper limb sensorimotor dysfunction; local anesthetic allergy and recent continuous use of analgesics.

Design outcomes

Primary

Measure	Time frame
Diaphragmatic paralysis;	—

Secondary

Measure	Time frame
Time to anesthesia satisfaction after administration;	—

Countries

China

Contacts

Public ContactHongjie Xi

The Second Affiliated Hospital of Harbin Medical University

113038857@qq.com+86 18686719297

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026