Patients with ventilator-associated diaphragmatic dysfunction
Conditions
Interventions
experimental group:The stimulation intensity was 6-8 Ma, the stimulation frequency was 40 Hz, the treatment time was 15 minutes, twice a day
Sponsors
The First Affilated Hospital of Wannan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with oral mechanical ventilation, aged over 18 years old; 2. Patients with DE < 10 mm and DTF < 20% were selected by ultrasound measurement on the day of admission and daily morning rounds; 3. Patients with cardiac function above grade IV, no serious renal insufficiency and good nutritional status; 4. Informed consent was signed by family members of patients.
Exclusion criteria
Exclusion criteria: 1. Contraindications of phrenic nerve stimulation (cardiac pacemaker, serious arrhythmia, pneumothorax, active pulmonary tuberculosis, pleural adhesion thickening, etc.); 2. Patients with pregnancy and mental illness; 3. Lack of window to see diaphragm thickness and mobility, such as patients with thoracoabdominal wound not allowed to use ultrasound; 4. Patients with high intra-abdominal pressure; 5. During mechanical ventilation, glucocorticoid and aminoglycoside antibiotics were used; 6. Patients with sepsis, hemodynamic instability and ejection fraction less than 30%.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm Thickening Fraction;Diaphragm Excursion; | — |
Countries
China
Contacts
Public ContactPeng Zhang
The First Affilated Hospital of Wannan Medical College
Outcome results
None listed