Lumbar disease
Conditions
Interventions
quadratus lumbar muscle block group:0.375% ropivacaine 0.3ml/kg
placebo control group:the equal dose normal saline
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Volunteer to participate in this trial and sign an informed consent instruction; 2) Age 40~70 years old; 3) Elective multi-segment lumbar spine surgery; 4) American Association of Anesthesiologists (ASA) physical condition classification I to III.
Exclusion criteria
Exclusion criteria: 1) Any cerebrovascular accident occurred within 3 months, such as stroke, transient ischemic attack (TIA), etc.; 2) History of cardiac insufficiency or echocardiogram showing EF<30%; severe sinus bradycardia (HR<50bpm); II or III degree atrioventricular block; active heart disease (acute myocardial infarction, unstable angina, etc.). 3) Dementia state or severe cognitive dysfunction; 4) Poor surgical anesthesia experience; 5) Abnormalities of nervous system, endocrine system, liver and kidney function; 6) There is a history of allergy to the drug being studied. 7) Past medical history of chronic pain; 8) History of opioid abuse or addiction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain scores;the first compression time of the electronic analgesic pump;infection;get out of bed time;Intestinal ventilation time;in-hospital time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total opioid consumption;the compression times of electronic analgesia pump;blood pressure and heart rate;infusion and transfusion;blood loss;urine volume;Nausea and vomiting;the duration time of surgery;the duration time of anesthesia;the time of awakening ;agitation of awakening period;Hypoxic saturation;delirium of Awakening period; | — |
Countries
China
Contacts
Public ContactZuo Chun Long
Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed