postoperative analgesia
Conditions
Interventions
Control group:0.5% ropivacaine 0.3ml/kg paravertebral block was given
esketamine group:0.5% ropivacaine 0.3ml/kg with esketamine 0.5mg/kg
Sponsors
The Second Affiliated Hospital of Nantong University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65; 2, ASA I ~ III level; 3. Pulmonary tumor surgery under general anesthesia, including wedge resection of lung and lung segment Resection, partial pulmonary resection, lobectomy and radical resection of unilateral lung cancer; 4. Plan to stay in hospital >= 48 hours after surgery.
Exclusion criteria
Exclusion criteria: 1.Have a history of allergy or contraindication to ropidocaine, ketamine, or nonsteroidal anti-inflammatory drugs (NSAIDs) (severe risk of elevated blood pressure and intracranial pressure, poorly controlled or untreated hypertension, untreated or undertreated hyperthyroidism, or gastrointestinal bleeding); 2.Have mental illness and other chronic pain; 3.Unable to read and write Chinese, communication barriers; 4.Emergency surgery or trauma patients; 5.Previous history of thoracotomy or intraoperative knowledge;Additional intercostal incisions were needed during the operation. 6.Admitted to ICU after surgery; 7.Unwillingness to use intravenous analgesia pumps and refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morphine consumption 24h after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS scores;the time of first remedial analgesia;Recovery quality score; | — |
Countries
China
Contacts
Public ContactBoxiang Du
The Second Affiliated Hospital of Nantong University
Outcome results
None listed