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Effects of GPIIbIIIa receptor antagonist duration on the prognosis of primary PCI in acute ST-segment elevation myocardial infarction with high thrombus burden

Effects of GPIIbIIIa receptor antagonist duration on the prognosis of primary PCI in acute ST-segment elevation myocardial infarction with high thrombus burden

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100042596
Enrollment
Unknown
Registered
2021-01-24
Start date
2019-01-01
Completion date
Unknown
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ST-segment elevation myocardial infarction

Interventions

Duration < 24 hours vs. duration 24-48 hours:N/A

Sponsors

Guangdong Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Definite STEMI for age >= 18 years; 2. Patients planned to undergo primary percutaneous coronary intervention (pPCI); 3. Intraoperative angiography showed high thrombus burden (thrombus score >= 3 points). Thrombosis Score: 0 points, no thrombus; 1 point, fuzzy thrombus shadow; 2 points, confirmed thrombus image, the length is less than 1/2 of the inner diameter of the blood vessel; 3 points, confirmed thrombus, the length is between 1/2 to 2 times the inner diameter of the blood vessel; 4 points, the determined thrombus length is greater than 2 times the inner diameter of the blood vessel; 5 points, blood clots cannot be assessed for blood clots.

Exclusion criteria

Exclusion criteria: 1. Past history of coronary artery bypass graft; 2. The criminal vessel is the left main trunk; 3. The offender's blood vessel is occluded or narrowed in the stent; 4. Killip grade IV; 5. History of rheumatic immune diseases; 6. Malignant tumor patients; 7. History of contrast agent allergy; 8. Life expectancy is less than 6 months; 9. Patients with recent active bleeding.

Design outcomes

Primary

MeasureTime frame
Major adverse cardiovascular events;

Secondary

MeasureTime frame
Left ventricular remodeling;Bleeding;

Countries

China

Contacts

Public ContactHaojian Dong

Guangdong Provincial People's Hospital

donghaojian@sina.com+86 13711012377

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026