Effect of etomidate and propofol mixture in elderly patients with hypertension

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100042584

Enrollment

Unknown

Registered

2021-01-23

Start date

2021-03-01

Completion date

Unknown

Last updated

2023-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anethesia

Interventions

group E:The anesthesia was performed with etomidate

group P:The anesthesia was performed with propofol

group E+P:The anesthesia was performed with etomidate+propofol

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >= 60 years; 2. Patients with hypertension, patients with regular hypertension treatment, blood pressure <140/90 MMHG. 3. body mass index(BMI) between 18 and 25; 4. No other history of contagion; 5. ASAII or III; 6. No history of abnormal anesthesia or delayed recovery (delayed recovery from anesthesia more than 2h).

Exclusion criteria

Exclusion criteria: 1. Shock, severe dehydration and electrolyte disturbance; 2. Patients with neuromuscular disorders; 3. Any allergy to the medications to be used in the study; 4. History of obstructive sleep apnea syndrome; 5. Refused to written informed consent; 6. Patients with difficult airway; 7. Known adrenal insufficiency.

Design outcomes

Primary

Measure	Time frame
blood pressure;heart rate;respiratory rate;saturation of pulse oxygen;	—

Secondary

Measure	Time frame
Awake time;	—

Countries

China

Contacts

Public ContactZhanjie Ren

WeiFang Madical University

lchmz@wfmc.edu.cn+86 13516385010

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026