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EGFR regulates the molecular mechanism the activation and apoptosis of CD4+ T lymphocyte in sepsis through Glut1

EGFR regulates Warburg metabolism through Glut1 and affects the apoptosis of CD4+ T lymphocytes in sepsis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100042571
Enrollment
Unknown
Registered
2021-01-23
Start date
2021-01-23
Completion date
Unknown
Last updated
2021-05-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Sepsis group:none
healthy control group:Nil

Sponsors

Affiliated Hospital of Guangdong Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients or family members gave informed consent to the study and signed the informed consent form 2. Healthy people in the physical examination center and inpatients with sepsis 3. Unlimited men and women, over 18 years old.

Exclusion criteria

Exclusion criteria: 1. With severe heart, liver, kidney and hematopoietic diseases; 2. Patients with malignant tumors; 3. Suffering from central nervous system and mental illness before surgery.

Design outcomes

Primary

MeasureTime frame
CD4+ T lymphocytes;

Countries

China

Contacts

Public ContactTang Jing

Guangdong Medical University

tanglitangjing@126.com+86 13189091282

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026