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Effect of dynamic positive end-expiratory pressure guided by driven pressure on postoperative atelectasis

Effect of dynamic positive end-expiratory pressure guided by driven pressure on postoperative atelectasis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042568
Enrollment
Unknown
Registered
2021-01-23
Start date
2021-01-21
Completion date
Unknown
Last updated
2021-05-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atelectasis

Interventions

Blank group:Positive end-expiratory pressure is zero
Control group:Positive end expiratory pressure of fixed 6cmH2O
Experimental group:Positive end-expiratory pressure guided by driving pressure

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients >= 65 years, undergoing elective laparoscopic surgery, expected to last >= 2h.

Exclusion criteria

Exclusion criteria: American Society of Anesthesiologists (ASA) physical status IV,history of severe chronic obstructive pulmonary disease (COPD, GOLD grades III or IV), history of severe or uncontrolled bronchial asthma, history of severe restrictive pulmonary disease, pulmonary metastases, history of any thoracic surgery, need for thoracic drainage before surgery, renal replacement therapy prior to surgery, congestive heart failure (NYHA grades III or IV) and lack of patients consent.

Design outcomes

Secondary

MeasureTime frame
Postoperative pulmonary complications;Blood gas analysis;—

Primary

MeasureTime frame
Lung ultrasound score;—

Countries

China

Contacts

Public ContactJing Yan Lin

Department of Anesthesiology, affiliated Hospital of North Sichuan Medical College

419931094@qq.com15983771119

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026