Uncovering the pathogenesis of generalized pustular psoriasis based on single-cell RNA sequencing

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100042529

Enrollment

Unknown

Registered

2021-01-23

Start date

2021-02-01

Completion date

Unknown

Last updated

2021-05-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

generalized pustular psoriasis

Interventions

GPP with il36rn mutation vs GPP without il36rn mutation:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients wtih generalized pustular psoriasis.

Exclusion criteria

Exclusion criteria: 1.Oral administration of retinoic acid, glucocorticoid, immunosuppressant and other drugs in the 4 weeks before the study; 2.Use of any topical medication in a large area within 2 weeks; 3.Combined with system infection; 4.combined with liver, lung disease or other systemic diseases.

Design outcomes

Primary

Measure	Time frame
RNA sequencing;	—

Countries

China

Contacts

Public ContactSheng Wang

Department of Dermatology, West China Hospital, Sichuan university

wangsheng1892@126.com+86 18980602125

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026