Non-small cell lung cancer
Conditions
Interventions
Gold Standard:If the tissue is available, it is the reference standard
if the tissue is unavailable, the pleural effusion cell blocks will be the reference standard.
cell 
blocks, 
sediment, 
PCR-based 
multi-gene 
(EGFR, 
KRAS, 
BRAF, 
NRAS, 
PIK3CA, 
ALK, 
ROS1,RET, 
MET)mutation 
Sponsors
Beijing Chest Hospital Affiliated to Capital Medical University / Beijing Chaoyang Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. NSCLC patients diagnosed by cytology or histopathology; Newly diagnosed or previously treated patients; 2. Patients who can obtain 100 ml pleural effusion samples through pleural puncture and drainage.
Exclusion criteria
Exclusion criteria: 1. Patients with multiple primary tumors and other tumors; 2. Non primary NSCLC patients; 3. The researcher's judgment may affect the clinical research and the judgment of research results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pleural effusion cell block PCR-multi-gene detection;pleural effusion cell sediment PCR-multi-gene detection;pleural effusion supernatant PCR-multi-gene detection; | — |
Countries
China
Contacts
Public ContactNanying Che
Beijing Chest Hospital Affiliated to Capital Medical University
Outcome results
None listed