Study on standardized use of topical antibiotics eye drops before cataract surgery

Efficacy of Preoperative Application of Topical 0.5% Levofloxacin Recommended by Chinese Guideline in Cataract Patients

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100042499

Enrollment

Unknown

Registered

2021-01-22

Start date

2021-02-18

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endophthalmitis after cataract surgery

Interventions

1-day group:One group receive topical 0.5% levofloxacin eyedrops six times a day for 1 day

2-day group:One group receive topical 0.5% levofloxacin eyedrops four times a day for 2 days

3-day group:One group receive topical 0.5% levofloxacin eyedrops four times a day for 3 days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 723 cases of senile cataract undergoing phacoemulsification with posterior chamber intraocular lens implantation in our hospital from 2021 to 2022 are inlcuding.

Exclusion criteria

Exclusion criteria: 1. Those who had used antibiotics locally or systematically within 6 months; 2. Allergic to any component of the study drug; 3. Combined with lacrimal duct obstruction, glaucoma, blepharoplasty, inverted eyelashes and other eye diseases; 4. Severe heart, lung, liver and kidney dysfunction; 5. Systemic or other drugs that affect the efficacy evaluation.

Design outcomes

Primary

Measure	Time frame
Aqueous humor level of levofloxacin;	—

Secondary

Measure	Time frame
Conjunctival culture;	—

Countries

China

Contacts

Public ContactJing Feng

Department of Ophthalmology, Beijing Chaoyang Hospital, Capital Medical University

drfengj@gmail.com+86 18610240524

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026